Smoking could play an immediate role in the introduction of schizophrenia and must be looked into, scientists say.
They at King's College London say people who smoke may get the disorder and also at a more youthful age.
- 57% of individuals with psychosis were already people who smoke once they had their first psychotic episode
- Daily people who smoke were two times as prone to develop schizophrenia as non-people who smoke
- People who smoke developed schizophrenia last year normally
The argument is when there's a greater rate of smoking before schizophrenia is identified, then smoking isn't just a situation of self-medication.
Dr James MacCabe, in the Institute of Psychiatry, Psychology and Neuroscience at King's, stated: "It's tough to establish causation [with this kind of study], what we are wishing this does is actually open our eyes to the chance that tobacco might be a causative agent in psychosis, so we hope this can then result in other research and clinical tests that will assistance to provide firmer evidence."
Clearly most people who smoke don't develop schizophrenia, however the scientists believe that it is growing the danger.
The general incidence from the condition is a in each and every 100 people normally, which might be elevated to 2 per 100 by smoking.
The scientists stated nicotine changed quantity of a brain chemical dopamine, which was already suggested as a factor within the psychosis.
Prof Michael Owen, the director from the Institute of Mental Medicine at Cardiff College, stated the scientists had designed a "pretty strong situation" that smoking could raise the chance of schizophrenia.
"The truth is it's very difficult to prove causation with no randomised trial, but you will find lots of reasons already for focusing on public health measures very energetically in the psychologically ill."
The charitable organisation Re-think Mental Illness stated: "We all know that 42% of cigarettes smoked in England are by individuals with mental health issues, and thus any new findings concerning the outcomes of smoking and psychosis is really a potential worry.